Latest News

5-Jul-2008 | Silicos launches new website.: Silicos announces the update of both the layout and the content of its website. After the initial technology development phase, Silicos is now ready to take the next steps along its path to becoming a valuable partner in drug discovery and design. As such, the redesigned site is more in line with the increased focus of Silicos on the application of its technology in both fee-for-service work and internal drug discovery projects. Therefore a new part of the website is especially dedicated to the internal drug discovery projects. Under the discovery section, information will be given about the status of Silicos' discovery pipeline.
May-2008 | Movetis and Silicos start collaboration.: Movetis and Silicos entered into a collaboration based on the potential of Silicos' technology for building predictive models. The goal of the project is to train a specific model, using the Spectrophores™ technology, for the prediction of the steady state blood plasma ratio for chemical entities.
Spring-2008 | Silicos expands its team.: To support its continuous growth, Silicos has strengthened its team with two modelers and one biologist. Both modelers, Matthias Mohr and Sandro Boland, have industrial experience in drug design and modeling. Their expertise will be used in both internal drug discovery projects and in specific fee-for-service projects.
Furthermore, as Silicos plans to bring its internal projects further in the discovery pipeline, a small screening facility will be set up to support the lead optimization. To this end Sofie Ignoul, a biologist, was hired to initiate the small laboratory. In the initial phase this will be in close collaboration with BioMed from the University of Hasselt.
Apr-2008 | Silicos publishes Pharao application.: Silicos has published the results of the implementation and retrospective testing of its pharmacophore-based tool, Pharao in Journal of Molecular Graphics and Modeling. Pharao is a pharmacophore-based scoring method that was developed to act as a virtual screening tool to retrieve molecules from different compound libraries and to perform pharmacophore-based clustering. The method is flexible so that it can also be used to guide the search for new molecules in de novo design algorithms or in other computer-assisted applications within the field of drug discovery. Pharao is an acronym for Pharmacophore Alignment and Optimization.
Jan-2008 | In Silico Biosciences and Silicos start collaboration: In Silico Biosciences has engaged Silicos in a multi-target virtual screening experiment to search for small molecule compounds that show desired activities against a panel of undisclosed targets. Silicos will apply its Spectrophores™ technology to build reliable virtual screening models for each of the targets and combine the models to find compounds with the expected activity profile.
Jan-2008 | UCB and Silicos start collaboration: UCB and Silicos entered into a collaboration to evaluate the potential of Silicos' technology for building predictive models. The goal of the project is to train specific models of which the predictive qualities can be assessed in UCB's early-phase drug discovery projects.